Cells
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How To Amp Up Energy In Your Skin Cells – Because, Yes, It’s Possible
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You may or may not already know this, but your cells require a constant supply of energy to function properly. Here's how to get them that energy.

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Fibroblast Activation Protein Is Overexpressed on Both Stromal and Epithelial Cells Before Pancreatic Ductal Adenocarcinoma: Implications for Early Diagnosis on 68Ga-FAPI-PET/CT
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The 5-year survival for pancreatic ductal adenocarcinoma (PDAC) exceeds 74% if diagnosed at stage I; however, this represents just 12% of resected cases.1 ...

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Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis
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Pancreatic endocrine cells are systematically altered in pancreatic ductal adenocarcinoma, defined as cancer-associated endocrine cells, in which pancreatic ...

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Acquisition of epithelial plasticity, and the potential origins of biphenotypic cells in chronic liver injury
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Gribben C, Galanakis V, Calderwood A, et al. Acquisition of epithelial plasticity in human chronic liver disease. Nature 2024;630:166–176

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Gluten-Dependent Activation of CD4+ T Cells by MHC Class II–Expressing Epithelium
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The gut lining actively participates in the activation of immune cells in celiac disease.

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Unveiling Cancer-Related Metaplastic Cells in Both Helicobacter pylori Infection and Autoimmune Gastritis
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Helicobacter pylori infection and autoimmune gastritis give rise to similar metaplastic cell phenotypes. One metaplastic subtype, common to both settings, ...

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King Abdulaziz University launches second edition of scientific forum on stem cells
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JEDDAH— King Abdulaziz University launched the second edition of the Stem Cell Scientific Forum, which was organized by the King Fahd Center ...

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Myosin Vb Traffics P-Glycoprotein to the Apical Membrane of Intestinal Epithelial Cells
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The authors use animal models, human biopsy samples, and human cells to demonstrate that MYO5B traffics the drug transporter P-glycoprotein to the apical ...

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Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease
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Despite the success of the anti-integrin antibody vedolizumab, few patients experience a sustained response. A comprehensive framework of nonresponse ...

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How Cells Resist the Pressure of the Deep Sea
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To study the cell membranes of deep-sea animals, the biochemist Itay Budin (center) joined forces with marine biologists Steve Haddock (right) and Jacob ...

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