The prevalence of Helicobacter pylori has decreased from 52.6% (95% confidence interval, 49.6%–55.6%) before 1990 to 43.9% (95% confidence interval, 42.3%–45.5%) during 2015 to 2022 in adults, but not in children and adolescents, concomitant with a decrease of gastric cancer incidence globally and in various countries where the prevalence of Helicobacter pylori infection has declined.
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