Pancreatic
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Fibroblast Activation Protein Is Overexpressed on Both Stromal and Epithelial Cells Before Pancreatic Ductal Adenocarcinoma: Implications for Early Diagnosis on 68Ga-FAPI-PET/CT
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The 5-year survival for pancreatic ductal adenocarcinoma (PDAC) exceeds 74% if diagnosed at stage I; however, this represents just 12% of resected cases.1 ...

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Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis
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Pancreatic endocrine cells are systematically altered in pancreatic ductal adenocarcinoma, defined as cancer-associated endocrine cells, in which pancreatic ...

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Pancreatic Cancer–Induced Metabolic Dysregulation Syndrome: Clinical Profile, Proposed Mechanisms, and Unanswered Questions
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The relationship between pancreatic ductal adenocarcinoma (PDAC) and diabetes mellitus (DM) is well known. However, recent studies reveal more extensive, ...

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Dual Targeting of Syndecan-1 and Glucose Transporter-1 With a Novel Lipid-Based Delivery System Enhances Therapeutic Efficacy and Overcomes Chemoresistance in Pancreatic Ductal Adenocarcinoma
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Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with limited treatment options and a 5-year survival rate of just 12.8%.1 Early ...

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Comments on “Diagnosis and Management of Pancreatic Cysts”
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The recent review on pancreas is extremely timely, succinct, and highly informative.1 The investigators are leaders in the field with seminal contributions ...

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Organoids for functional precision medicine in advanced pancreatic cancer
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Patient-derived organoids (PDO) are promising tumor avatars that could enable ex vivo drug tests to personalize patients’ treatment in the frame of ...

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