Bowel
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Adding Linaclotide To Help With Bowel Prep
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H Xu et al. Journal of Gastroenterology and Hepatology; 2024: https://doi.org/10.1111/jgh.16734. Application of linaclotide in bowel preparation ...

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Beyond the Norm: Epidemiology of Irritable Bowel Syndrome and Mental Health Among Sexual and Gender-Diverse Young Adults in a Large Representative Cohort
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Irritable bowel syndrome (IBS) is a common chronic disorder of gut–brain interactions associated with substantial disease burden and reduced quality of ...

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Targeting the Interleukin 23 Pathway in Inflammatory Bowel Disease
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Interleukin (IL) 23, a member of the IL12 family of cytokines, maintains intestinal homeostasis, but is also implicated in the pathogenesis of inflammatory ...

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Gut Pathobiont–Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis–Associated Inflammatory Bowel Disease
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The study reveals that gut pathobiont-derived outer membrane vesicles might play a crucial role in promoting liver inflammation and fibrosis in primary ...

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Inflammatory Markers at Birth and Risk of Early-Onset Inflammatory Bowel Disease
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The development of inflammatory bowel disease (IBD) may be preceded by a long preclinical phase characterized by several disease-associated immunologic ...

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Prevotella Is Associated With Sex-Based Differences in Irritable Bowel Syndrome
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Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders of the developed world. Sex differences in IBS have been well documented ...

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Molecular Mechanisms Underlying Loss of Vascular and Epithelial Integrity in Irritable Bowel Syndrome
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This study demonstrates that intestinal permeability alterations are involved in the development of intestinal and extra-intestinal symptoms in irritable ...

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Management of Small Bowel Crohn’s Disease Strictures: To Cut, to Stretch, or to Treat Inflammation?
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This patient’s case history (void of protected health information) was discussed in a multidisciplinary meeting including adult gastroenterologists (CL, ...

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It Runs in the Family: What Studying Unaffected Individuals in Simplex and Multiplex Families Tells Us About Inflammatory Bowel Disease Development
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Inflammatory bowel disease (IBD) is a partially heritable condition. To date, more than 600 genetic regions have been found to be associated with IBD. We ...

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Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4+ T Cells as Predictors for Response to Integrin α4β7–Blocking Therapy in Inflammatory Bowel Disease
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Despite the success of the anti-integrin antibody vedolizumab, few patients experience a sustained response. A comprehensive framework of nonresponse ...

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