Sessile serrated lesions (SSLs) are important precursors to colorectal cancer (CRC). It is estimated that 20% to 30% of CRCs arise from SSLs through a pathway distinct from the traditional adenoma-carcinoma sequence. The US Multi-Society Task Force on CRC recommends colonoscopy or fecal immunochemical test (FIT) as tier 1 tests for CRC screening in average-risk individuals.1
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